cancer

Researchers integrate scRNA-seq, spatial transcriptomics, and histology imaging data to show that spatial cellular architecture predicts glioblastoma prognosis.

Anne L’Huillier, Pierre Agostini, and Ferenc Krausz received this year’s Physics award for creating tools for studying the world of electrons, with future applications in medical diagnostics.

An often overlooked property of the tumor environment shapes T cell function and may improve T cell therapies.

Vaginal dysbiosis has long been a taboo subject, but studying and optimizing the vaginal microbiome could be a game changer for women's health.

Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.

Researchers unravel the mystery of epithelial to mesenchymal transition in acute lymphoblastic leukemia with co-culture techniques, CRISPR-screening, and RNA sequencing.

Scientists established an epigenetic mouse model for glioma, providing insight into how epigenetics can initiate cancer.

This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.

Researchers took aim at mucins, glycoproteins that protect cancer cells from drugs and the immune response, and engineered a revolutionary targeted tool for oncology and beyond.

A new mouse model shows that the Myc protein has complex effects on aging and cancer.

Researchers connect a tumor’s leading edge transcriptional profile to poor survival outcomes across cancer types. 

Using a mouse model of breast cancer brain metastasis, researchers showed that tumor cells require fatty acid synthesis to grow, which offers a potential therapeutic target.

Researchers turn to high resolution sequencing to explain recurrent melanoma mutations caused by UV exposure.

Researchers built a 3D glioblastoma model to study therapeutic resistance and improve drug screening systems.