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biochemistry

A 96-well microplate containing serial dilutions of stained samples.
Expanding Sample Analysis While Shrinking Instrument Footprints
The Scientist Staff | Sep 1, 2023 | 2 min read
Cutting-edge analytical instruments provide researchers with improved analysis capabilities in a compact design.
Illustration showing how this new novel nanotechnology simultaneously ‘fishes’ for multiple viruses or viral variants using different DNA nanobait that are designed to target specific viral sequences.
Fishing for Viruses With DNA Nanobait
Danielle Gerhard, PhD | Sep 1, 2023 | 2 min read
Scientists developed a novel nanotechnology that simultaneously detects multiple viruses from patient samples in less than an hour.
Lipofuscin autofluorescence was quenched using EverBrite TrueBlack® Hardset Mounting Medium®, allowing effective visualization of glial cells (GFAP antibody stain, cyan) and cell nuclei (magenta) in human cerebral cortex cryosections.
Stepping Out of the Background
The Scientist’s Creative Services Team and Biotium | 4 min read
New developments in non-specific fluorescence quenching offer researchers clearer pictures and more multiplexing possibilities.
Oops, speech bubble.
The Oligo Was a No Go
Danielle Gerhard, PhD | Sep 1, 2023 | 2 min read
As soon as Melanie McConnell added the wash buffer to her sample, she knew she had made a mistake.
Conceptual image of hair loss showing trees in the shape of a human head at various seasonal stages of shedding their leaves.
Islands of Knowledge: Hairy Skin Moles Make Their Mark
Iris Kulbatski, PhD | Aug 7, 2023 | 3 min read
Skin moles that sprout thick, long hairs produce signaling molecules that stimulate hair follicle stem cells to initiate new hair growth. This discovery may make baldness a thing of the past.
The Ins and Outs of LC-MS
The Ins and Outs of LC-MS
Deanna MacNeil, PhD | 4 min read
From proteomics to pharmacokinetics, researchers turn to advances in liquid chromatography and mass spectrometry to identify and quantify components in different samples.
 Dive into Cryo-EM’s History, Milestones, and Insights.
Cryo-EM: Building on a History of Invention and Innovation
Thermo Fisher Scientific | Aug 2, 2023 | 1 min read
From humble yet ingenious beginnings to Nobel recognition, cryogenic electron microscopy (cryo-EM) provides insights into scientific questions that other technologies are unable to answer.
Image of unfolded protein
My Protein Didn't Fold and Neither Did I
Meenakshi Prabhune, PhD | Aug 1, 2023 | 2 min read
When Gaurav Ghag realized that he had replicated a calculation error in every experiment during four years of his graduate research, he initially thought that his career had unraveled with his protein.  
The Intricacies of Western Blotting
The Intricacies of Western Blotting
The Scientist’s Creative Services Team | 1 min read
In this webinar, R. Hal Scofield discusses hints and tips on how to generate clean and reproducible western blot data, even in tricky situations. 
Image of coral reef
A Probiotic to Protect Caribbean Corals
Mariella Bodemeier Loayza Careaga, PhD | Aug 1, 2023 | 2 min read
A bacterial strain from healthy corals could slow the progression and prevent transmission of the destructive stony coral tissue loss disease in the wild.
Green-themed conceptual illustration of a human profile with abstract patterns that represent smelling.
Disease Scent Signatures Disclose What the Nose Knows
Iris Kulbatski, PhD | Jun 12, 2023 | 4 min read
Researchers redefine the lost art of smelling illness using one woman’s exquisitely sensitive nose.
Technique Talk: The Fundamentals of Mass Spectrometry-Based Proteomics
Technique Talk: The Fundamentals of Mass Spectrometry-Based Proteomics
The Scientist’s Creative Services Team | 1 min read
Learn the basics of proteomics analysis and nanoLC-MS/MS data acquisition.
Saccharomyces cerevisiae 
Waves of Macromolecule Production During the Cell Cycle
Mariella Bodemeier Loayza Careaga, PhD | Jun 1, 2023 | 3 min read
In individual yeast cells, essential biosynthetic processes peak at different times in the cell cycle, revealing a temporal dynamic once thought limited to DNA synthesis.
a yellow-ish fish skull is held up by metal prongs, with a rack of other museum collection items in the background
Fossilized Fish Teeth Could Be Earliest Evidence of Cooking
Katherine Irving | Nov 14, 2022 | 2 min read
Study authors say the teeth, dated around 780,000 years old, push back the date humans are known to have engaged in cooking by more than 600,000 years. 
Droplet of DNA lysate
Optimizing Sample Homogenization
The Scientist’s Creative Services Team and Bertin Technologies | 3 min read
Discover how the latest homogenization technology improves and simplifies the processing of any biological sample.
Rows of soybean plants with green leaves beneath a partially clouded sky with the rising sun in the background.
As Carbon Dioxide Goes Up, Plants’ Nutrient Content Declines
Dan Robitzski | Nov 3, 2022 | 5 min read
Abundant environmental CO2 can increase plant biomass and photosynthesis, but it has downsides for agriculture and ecosystems, a growing body of research finds.
an&nbsp;<em>Aedes aegypti&nbsp;</em>mosquito, black with white dots and stripes on its joints and body, sitting on a person&#39;s skin and feeding.&nbsp;
Smelly Skin Compounds Draw Mosquitoes to Some People More than Others
Katherine Irving | Oct 19, 2022 | 3 min read
People with more carboxylic acids in their body odor are more attractive to mosquitoes, a study finds.
Learn how recombinant proteins move the diagnostic industry forward
Emergent Recombinant Proteins in Clinical Diagnostics
Scripps Laboratories | 1 min read
A new era of reliable recombinant proteins makes it possible for researchers to replace tissue-derived biomarkers in a variety of diagnostic assays.
Tree with many scattered branches.
Scientists Resurrect Ancient Rubiscos to Understand Their Evolution
Alejandra Manjarrez, PhD | Oct 14, 2022 | 5 min read
A team proposes that the addition of a small accessory subunit to the carbon-fixing enzyme was key to improving its catalytic properties and specificity to CO2.
Illustration of the winners of the 2022 Nobel Prize in Chemistry
Biocompatible Reactions In Living Cells Garner Chemistry Nobel
Katherine Irving | Oct 5, 2022 | 4 min read
This year’s award recognizes Carolyn Bertozzi, Morten Meldal, and K. Barry Sharpless for developing click chemistry and bioorthogonal chemistry.
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