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neuroscience

This image depicts the fruit fly nerve cord connectome. It highlights 930 neurons, a subset of the full set of reconstructed neurons.
The Expansion of Volume Electron Microscopy
Danielle Gerhard, PhD | Sep 8, 2023 | 6 min read
A series of technological advancements for automation and parallel imaging made volume electron microscopy more user friendly while increasing throughput.
Illustration showing how iGluSnFR3, tracks glutamate release at the synapse level. Upon binding to glutamate, the reporter changes its conformation, intensifying the signal of its fluorescent protein.
Infographic: How a Glutamate Sensor Tracks Synapses
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 1 min read
A third generation glutamate sensor with a fluorescent readout offers insights into neuronal communication.
Mosaic brain image
Science Summarized: The Mosaic Brain
The Scientist’s Creative Services Team | 1 min read
Mutations that accumulate as one ages contribute to various neurological disorders.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Digital illustration of a brain, constructed by tiny dots and lines. Most dots and lines are teal-colored; others are green, yellow, red, and purple to denote areas of activity.
What Was the First Animal to Evolve a Brain?
Ida Emilie Steinmark, PhD | Sep 1, 2023 | 2 min read
In the absence of a precise definition of brain, pinning down its origins is difficult. But scientists have a theory.
TSS
Genomes Across the Tree of Life
The Scientist’s Creative Services Team | 2 min read
Researchers turn to unique eukaryotes to better understand how DNA is organized in 3D space.
The image shows round-shaped glial cells in red and elongated neuronal cells in green surrounding the glial cells.
How Stress Inflames the Gut
Mariella Bodemeier Loayza Careaga, PhD | Sep 1, 2023 | 2 min read
In mice, chronically high levels of stress hormones worsen bowel inflammation.
Colorful blue and pink low poly side view human brain illustration with connection dots isolated on bright blue background
Cancer Cells Need Fatty Acids to Survive in the Brain
Danielle Gerhard, PhD, Drug Discovery News | Aug 30, 2023 | 3 min read
Using a mouse model of breast cancer brain metastasis, researchers showed that tumor cells require fatty acid synthesis to grow, which offers a potential therapeutic target.
Translational Research for Neural Implants
Translational Research for Neural Implants 
The Scientist’s Creative Services Team | 1 min read
John Donoghue and Vasiliki (Vasso) Giagka will discuss the latest bioengineering advances for implantable devices that treat neurological disorders.
The image illustrates the relationship between the brain and gut in humans.
A Novel Tool to Explore the Gut-brain Connection
Anna Napolitano, PhD | Aug 28, 2023 | 3 min read
Scientists used a vibrating capsule to assess people’s gut sensitivities and understand how the brain interprets these signals.  
A light gray mouse against an orange background listens to tiny headphones
Journey to the Center of the Ear
Niki Spahich, PhD | Aug 28, 2023 | 5 min read
An aqueduct connecting the brain to the ear may make gene therapy for hearing loss less invasive.
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A Way with Words: Using Genomics to Dispel Stuttering Myths
The Scientist’s Creative Services Team | 1 min read
Filling in the gaps about the genetic risk factors of stuttering may help scientists shatter stigmas and discover new therapies.
MRI images of brains from patients with epilepsy
Defending against Dravet
Aparna Nathan, PhD | Aug 21, 2023 | 3 min read
Gene therapy may be the first step toward curing a rare genetic epilepsy.
Six black-and-white MRI images of a brain at different cross-sections.
Is DIANA fMRI Data Real?
Ida Emilie Steinmark, PhD | Aug 17, 2023 | 4 min read
New preprints failed to reproduce the buzzy new neuroimaging technique DIANA fMRI, but its inventor remains steadfast.
TSS
Immune Cells and ALS: A Balance Between Life and Death
The Scientist’s Creative Services Team | 1 min read
Understanding the role of immune cells in neurodegeneration may help scientists develop new diagnostic, prognostic, and treatment tools.
Professor Alexandra Whiteley and graduate student Autumn Matthews look at an image of a western blot on their laboratory computer.
An Ancient Viral Protein May Play a Key Role in ALS
Aditi Subramaniam, PhD | Aug 15, 2023 | 4 min read
Researchers find that UBQLN2 gene dysfunction causes a virus-like protein to accumulate in cells, which changes gene expression and may contribute to disease progression in amyotrophic lateral sclerosis (ALS).
Caenorhabditis elegans, a free-living transparent nematode (roundworm), about 1 mm in length.
The Body, Not the Brain, Regulates Sleep
Rebecca Roberts, PhD | Aug 15, 2023 | 3 min read
Genetic screens have revealed three peripheral tissue genes that regulate sleep. What does this mean for sleep research?
Neuronal network with electrical activity of neuron cells in 3D
How Do Neurons Work?
Jennifer Zieba, PhD | 6 min read
Neurons transmit information through the body via chemical signals and electrical impulses.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Surreal illustration of the mind, represented by a person-shaped iceberg. A scuba diver illuminates the dark side of the iceberg underwater with a flashlight.
Toward Better Biomarkers for Schizophrenia
Deanna MacNeil, PhD | Aug 7, 2023 | 3 min read
Researchers scratch the surface of schizophrenia susceptibility by uncovering DNA methylation differences in neonatal blood samples.
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