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Uncover Archived Expression Profiles in FFPE Samples
Uncover Archived Expression Profiles in FFPE Samples
Researchers can overcome RNA degradation challenges in preserved samples with an in situ hybridization-based single cell expression profiling assay.
Researchers can overcome RNA degradation challenges in preserved samples with an in situ hybridization-based single cell expression profiling assay.
single-cell RNA sequencing
Niche Interactions Lock Down Leukemia Cells
Deanna MacNeil, PhD | Sep 24, 2023 | 3 min read
Researchers unravel the mystery of epithelial to mesenchymal transition in acute lymphoblastic leukemia with co-culture techniques, CRISPR-screening, and RNA sequencing.
A How-to Guide for Planning Single Cell Gene Expression Studies
10x Genomics | Oct 21, 2022 | 1 min read
Follow the roadmap to successful single cell transcriptomic workflows and outputs.
How Fat Cells Help Kick Parasites Out of Mice: Study
Natalia Mesa, PhD | Oct 14, 2022 | 3 min read
Immune cells get a lot of shine when it comes to fighting infection, but it turns out that fat might be just as important for removing parasitic invaders.
Specific Brain Cells Linked to Parkinson’s Disease
Dan Robitzski | May 6, 2022 | 2 min read
Research identifies 10 types of dopamine-making neurons, one of which seems to die off during the disease.
Single-cell Secrets
The Scientist’s Creative Services Team | Oct 30, 2020 | 1 min read
Single-cell research reveals new insights into SARS-CoV-2, the opioid crisis, neurogenesis, and fertility.
The Scientist's LabTalk Podcast - Episode 2
The Scientist’s Creative Services Team | Oct 20, 2020 | 1 min read
Surviving Stress: The mysteries of neuronal survival and neurodegeneration
Worm Embryogenesis: Cell by Cell and Gene by Gene
Kerry Grens | Dec 1, 2019 | 2 min read
A single-cell map of C. elegans’s transcriptome during development finds cell lineages that start out genetically different and end up as cells of similar function and genetic profile.
Neural Cell Types Tied to Autism Identified in Single-Cell Study
Ruth Williams | May 16, 2019 | 3 min read
An RNA analysis of human brain cells reveals gene expression changes in cortical neurons and microglia linked to autism spectrum disorder (ASD).
2018 Top 10 Innovations
The Scientist Staff | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
Revealed: New Cortical Neuron Types
Ashley P. Taylor | Oct 31, 2018 | 2 min read
A pair of mouse studies describes neuronal subpopulations not identified before and some of their functions.
Integrating Multiple -Omics in Individual Cells
Sandeep Ravindran | Oct 1, 2018 | 8 min read
New techniques combine DNA, RNA, and protein information from single cells.
New Lung Cell Identified
Abby Olena, PhD | Aug 1, 2018 | 4 min read
The cell type was discovered via single-cell RNA sequencing of thousands of cells in mouse and human airways and may play a role in cystic fibrosis.
Live Cell Extractions
Ruth Williams | Oct 1, 2017 | 3 min read
Nanostraws that collect specimens from cells without killing them allow for repeated sampling.
A Selection of CRISPR Proof-of-Principle Studies
Kelly Rae Chi | Mar 1, 2017 | 7 min read
Advice on how to deploy the latest techniques in your own lab