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protein
A Protein-Rich Diet Helps Mice and Flies Sleep More Soundly: Study
Alejandra Manjarrez, PhD | Mar 24, 2023 | 3 min read
The effect appears to be mediated by a gut-secreted peptide that signals to neurons in the brain that modulate the response to mechanical vibrations.
2022 Top 10 Innovations
The Scientist Staff | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
CF® Dyes: Clearer Fluorescent Results
Biotium | 1 min read
CF® Dyes combine pegylation and sulfonation to create fluorescent dyes with better signal intensity, more solubility, and superior specificity.
New Gene Mutants Identified in Rare Motor Neuron Diseases
Clare Watson | Oct 17, 2022 | 2 min read
The discovery of gene variants in cases of hereditary spastic dysplasia could provide a diagnosis to affected families where no genetic cause could be found before.
Fungal Cold Adaptation Linked to Protein Structure Changes: Study
Patience Asanga | Sep 20, 2022 | 4 min read
Environmental pressure seems to spawn changes in the intrinsically disordered regions of enzymes in polar yeasts, allowing them to adapt to extreme cold.
Best Practices for Single-Cell Proteomics Using Mass Spectrometry
The Scientist’s Creative Services Team | 1 min read
In this webinar, Runsheng Zheng and Fernanda Salvato will discuss how to optimally examine single-cell proteomes through label-free, data-independent acquisition (DIA) mass spectrometry.
Infographic: Secret Lives of Neurodegeneration-Linked Proteins
Catherine Offord | Aug 1, 2022 | 5 min read
Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain.
Ancient Tooth Could Be Clue in Denisovan Migration Mystery
Andy Carstens | May 18, 2022 | 2 min read
The new fossil from Laos helps answer the question of how some people from Oceania carry DNA from the ancient hominin.
Optimizing Sample Homogenization
The Scientist’s Creative Services Team and Bertin Technologies | 3 min read
Discover how the latest homogenization technology improves and simplifies the processing of any biological sample.
Infographic: Short Protein Motifs’ Role in SARS-CoV-2 Infection
Conchita Fraguas Bringas and Jakob Nilsson | May 16, 2022 | 4 min read
Known as SLiMs, these stretches of up to 10 amino acids play notable roles in cell biology, including responses to viral invasion.
Viruses Target Super-Short Protein Motifs to Disrupt Host Biology
Conchita Fraguas Bringas and Jakob Nilsson | May 16, 2022 | 10+ min read
Only recently appreciated as critical components of cellular functions, unstructured stretches of amino acids called SLiMs are key to viral-host interactions.
An Introductory Guide to Proteomics
Sejal Davla, PhD | 5 min read
Deconstructing concepts, approaches, and data analysis in proteomics workflows.
Synthetic RNA Can Build Peptides, Hinting at Life’s Beginnings
Jef Akst | May 12, 2022 | 2 min read
Researchers engineered strands of RNA that can link amino acids together, suggesting a way that RNA and proteins may have emerged together to create the earliest forms of life.
DNA Nanopore Sequencing Adapted for Protein Sequence Comparisons
Sophie Fessl, PhD | Feb 14, 2022 | 3 min read
Researchers link a stretch of DNA to a peptide of interest and measure current changes as the molecule is pulled by a helicase through a nanopore.
Streamlined Purification Workflows for Biomolecule Production
Bio-Rad Laboratories | 1 min read
Researchers optimize chromatography-based workflows to purify biomolecules at scale.
Infographic: Reading Proteins with Nanopores
Sophie Fessl, PhD | Feb 14, 2022 | 1 min read
Adapting DNA nanopore sequencing to peptides allows researchers to identify single amino acid differences.
Gut Microbes Help Ground Squirrels Endure Hibernation
Alejandra Manjarrez, PhD | Jan 27, 2022 | 4 min read
By breaking down urea, the animals’ gut bacteria recycle nitrogen, which can be then used to build new molecules during prolonged fasting.
Using Single Cell Proteomics to Understand Human Health and Disease
The Scientist’s Creative Services Team and 10x Genomics | 1 min read
Miriam Merad and Harrison Specht will discuss how single cell proteomics complement other omics methods to provide insight into disease pathophysiology and treatment.
Protein Mediates Non-Genetic Inheritance of Growth Strategies
Catherine Offord | Jan 4, 2022 | 2 min read
An RNA-modifying enzyme passed to daughter cells during budding allows yeast cells to switch between faster- and slower-growing phenotypes.