protein structure

A team proposes that the addition of a small accessory subunit to the carbon-fixing enzyme was key to improving its catalytic properties and specificity to CO₂.

Three prizes were awarded to six researchers working across the life sciences on cellular organization, protein structure, and the genetic underpinnings of a chronic sleep disorder.

Known as SLiMs, these stretches of up to 10 amino acids play notable roles in cell biology, including responses to viral invasion.

Researchers demonstrate that the SARS-CoV-2 spike protein is more stable and binds the human ACE2 receptor with much higher affinity than the spike protein of its closest known relative, bat coronavirus RaTG13.

Folding@Home, currently focused on deciphering the workings of SARS-CoV-2, is the first project to have exascale-level computational muscle.

The UCLA researcher was lauded for figuring out how ATP synthase works.

Metagenomic sequence data boosts the power of protein modeling software to yield hundreds of new protein structure predictions.

See an animation that illustrates emerging insights into the inner ring structures of the nuclear pore complex.

Nature retracts a study six years after an investigation found that the protein structures it reported were fabricated.

Contrary to years of research suggesting otherwise, most aggregated proteins regain their shape and functionality following heat shock.

The gene-editing CRISPR/Cas9 system has three checkpoints to ensure it alters the right section of DNA.

Actin—the bones of the cell—has a preference for swirling into a counterclockwise pattern.

Computational tools take some of the cost—and guesswork—out of drug discovery.