organoids

Alysson Muotri launched brain organoids into outer space and found that microgravity enriches our understanding of brain development and disease.

Benedetta Artegiani and Delilah Hendriks formed a joint laboratory group to understand disease mechanisms and treatments through organoid models.

The organoids could one day be used to treat brain injuries in humans. 

By modifying a technique used to image single cells, researchers have managed to generate a super-resolution 3D image of a complete organoid in just seven seconds.

Analyzing organoids has proven slow and cumbersome for scientists. But a new technique may speed things up, producing 3D images of hundreds of organoids per hour.

The human cells, engineered to respond to blue light, influenced rat behavior when stimulated.

A single amino acid substitution in a protein causes increased neuron production in the frontal lobes of humans compared to Neanderthals—a tiny difference that could have given our species a cognitive edge, researchers say.

Disturbing circadian rhythms in organoids and mice increases intestinal tumor growth, findings that may explain a recent rise in colon cancer among young adults, the researchers behind the work say.

Controlling a growing tissue’s shape achieves deterministic and uniform patterning in intestinal organoids.

Marina Sanaki-Matsumiya figured out how to grow human somites in a dish through a process that mirrors the tissue’s development in the embryo.

The genes are involved in pacing the development of inhibitory and excitatory neurons. An imbalance in these two types of signaling is thought to play a role in autism.

A newly developed platform may one day replace cell culture and animal models to personalize cancer treatment.

Researchers are taking the concept of three-dimensional cell culture beyond single organoids to develop embryos from cells.