Alejandra Manjarrez, PhD | Oct 19, 2022 | 4 min read
Epigenetic events, such as methylation, during early brain development in mice occur in genomic regions associated with BMI in humans, according to a new study.
Obese mice that exercised while pregnant gave birth to pups that grew up free of the metabolic issues present in the adult young of sedentary obese mothers—possibly by staving off epigenetic changes to a key metabolic gene.
Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.
Altered gut microbiome composition in obese mice and human patients is linked with severity of disease after bone marrow transplantation, a study found.
Paul Cohen of the Rockefeller University describes his study of thousands of people, finding that the energy-burning tissue is tied to a lower risk of for several diseases, including type 2 diabetes, high blood pressure, and heart disease.
Physical activity, independent of diet, shifts the composition of bacteria in the intestines, spurring researchers to search for species that might provide benefits akin to working out.
Developing computational tools to analyze the reams of microbial sequencing data his lab generates, the UC San Diego microbiologist is a pioneer of microbiome research.