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next generation sequencing

Genetic engineering and digital technology concept.

A Machine Learning Tool Uncloaks the Hidden Sources of Cancer Cells

Rachael Moeller Gorman | Oct 5, 2023 | 4 min read

Researchers created a model that uses clinical testing data to locate the primary site of cancer cells with no known origin, likely improving survival.

Image of spatial transcriptomic spots superimposed onto a stained tissue section.

Poor Cancer Prognosis Associated with a Transcriptional Signature

Charlene Lancaster, PhD | Sep 11, 2023 | 4 min read

Researchers connect a tumor’s leading edge transcriptional profile to poor survival outcomes across cancer types.

The Scientist's Journal Club: Transcriptomics

The Scientist’s Creative Services Team | 2 min read

Scientists discuss their latest findings on immune cell dynamics, neurodegenerative disease risk factors, and rare cell types obtained from bulk and single cell RNA sequencing experiments.

Interrogating the Complexities of the Tumor Microenvironment

Alison Halliday, PhD, Technology Networks | May 19, 2023 | 5 min read

Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.

Genomic data. Dna test infographic, molecule structure genetic sequencing chart and chromosome architecture genealogy diagram, vector concept stock illustration

Unearthing Hidden Family Secrets: Tracing the Lineage of a Centuries-Old Grand-Mummy

Iris Kulbatski, PhD | Dec 13, 2022 | 3 min read

Researchers show how a toxic therapy helped identify a mummy using preserved DNA.

How Can Core Labs Help You Get Started with NGS?

The Scientist’s Creative Services Team | 1 min read

Next-generation sequencing (NGS) core facility scientists and researchers new to NGS discuss their fruitful collaborations, highlighting how to receive expert help from genomics facilities.

Uncovering Leprosy’s Genetic Recipe for Success

Nele Haelterman, PhD | Aug 17, 2022 | 3 min read

Researchers identify what makes certain people more likely to contract leprosy than others.

Researchers use bacterial whole genome sequencing to compare the phylogenetic relationship between environmental and clinical samples.

Aquatic Bacteria Reveal a Common Genetic Link to a Deadly Human Pathogen

Iris Kulbatski, PhD | Mar 7, 2022 | 5 min read

Researchers use genetic clues to track the spread of antibiotic resistant bacteria from the environment to patients.

Targeted DNA Sequencing: Probing for Answers

The Scientist’s Creative Services Team and Roche | 1 min read

A more focused investigation for more in-depth answers.

Gut Bugs May Help Centenarians Reach Their 100th Birthdays

Roni Dengler, PhD | Aug 30, 2021 | 3 min read

Centenarians have distinct microbiomes with species that produce unique bile acids, which may help thwart illness.

Ancient Humans Had Hepatitis B

Abby Olena, PhD | May 9, 2018 | 4 min read

Analyses of more than 300 ancient human genomes show that Hepatitis B virus has infected humans for at least 4,500 years and has much older origins than modern viral genomes would suggest.

Layered visual representation of multiomics

Integrate and Innovate with NGS and Multiomics

The Scientist’s Creative Services Team and Illumina | 6 min read

Researchers across disciplines combine layers of discovery obtained with accessible NGS-based multiomics approaches.

Q&A: Confirming Next-Gen Sequencing Results with Sanger

Tracy Vence | Oct 11, 2016 | 4 min read

Ambry Genetics CEO Aaron Elliott discusses his team’s recent analysis of 20,000 clinical next-generation sequencing panels.

Spiders, Prey Leave DNA

Bob Grant | Nov 30, 2015 | 1 min read

A study of black widow spiders suggests that the arachnids leave traces of their own genetic material and DNA from prey in their sticky webs.

Single Cell Sequencing in a Nutshell

Niki Spahich, PhD | 4 min read

By exploring the inner workings of individual cells, rather than averaging bulk populations, researchers identify rare and important cell subtypes.

TS Live: Genetic Time Machine

Bob Grant | Jun 12, 2015 | 1 min read

Piecing together scraps of DNA from a 400,000-year-old hominin femur

What’s Old Is New Again

Bob Grant | Jun 1, 2015 | 10+ min read

Revolutionary new methods for extracting, purifying, and sequencing ever-more-ancient DNA have opened an unprecedented window into the history of life on Earth.