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Fluorescently labeled neuron cell bodies in blue in the center compartment of a three-compartment microfluidic chamber grow through tiny grooves to enter the left and the right chambers, where they extend axons fibers, also shown in blue.

Visualizing Axon Pruning

Tiffany Garbutt, PhD | Oct 2, 2023 | 2 min read

During development, neurons trim hundreds of excess axons in an intricately coordinated destructive process.

MRI images of brains from patients with epilepsy

Defending against Dravet

Aparna Nathan, PhD | Aug 21, 2023 | 3 min read

Gene therapy may be the first step toward curing a rare genetic epilepsy.

<em >The Scientist</em>’s Journal Club: Neuroscience

The Scientist’s Journal Club: Neuroscience

The Scientist’s Creative Services Team | 1 min read

Scientists present the latest research on cortical neuronal networks, neuronal signaling, and amyloid-forming proteins.

The image shows a brain section of the mouse amygdala. Using fluorescent markers, the expression of synapses is shown in purple, while neurons are shown as red dots and the microRNA miR-483-5p is shown as green dots.

A Brain MicroRNA Curbs Anxiety

Mariella Bodemeier Loayza Careaga, PhD | Aug 1, 2023 | 2 min read

Upregulation of a specific microRNA in the brain lessened anxiety and reduced the expression of stress-related genes in mice.

In this transgenic ant pupa surrounded by wild type pupae, green fluorescence on top reveals olfactory sensory neurons. On the bottom, the expression of red fluorescent protein shows throughout the ant pupa body.

Spying on Transgenic Ants Reveals How Their Brains Respond to Alarm Odors

Alejandra Manjarrez, PhD | Jul 7, 2023 | 2 min read

By successfully creating transgenic ants for the first time, researchers discovered that danger-signaling pheromones activate a sensory hub in the ants’ brains.

Neurons traversing the brain with an area of red neurodegeneration

LabTalk Podcast - The New Era of Neurodegeneration Research

The Scientist’s Creative Services Team | 1 min read

Erdem Gültekin Tamgüney discusses the future of neurodegeneration research and his work exploring the link between stroke and Parkinson’s disease.

Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.

Short-lived Molecules Support Long-term Memory

Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read

A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.

Neurons (green) fire differently depending on whether the astrocytes (red) they are grown with are cultivated from people with or without fragile X.

Astrocytes Fuel Erratic Firing in Fragile X Neurons

Lauren Schenkman, Spectrum | May 30, 2023 | 4 min read

This new understanding could one day lead to targeted treatments.

The Brain Inside Out: Mapping the Nervous System Wiring

The Brain Inside Out: Mapping the Nervous System's Wiring

The Scientist’s Creative Services Team | 1 min read

An expert panel will describe their efforts to chart billions of neuronal connections and discuss how this data provides unparalleled insight into neuronal cell biology, signal processing, and behavior.

Rare Autism-Linked Mutation Starves Growing Neurons of Essential Nutrients

Lauren Schenkman, Spectrum | Apr 18, 2023 | 4 min read

The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.

Surface rendering of microscopy image showing two dendritic cells (green) communicating with a nociceptor neuron (violet).

How Cells in the Skin Team Up To Fight Pathogens

Rachael Moeller Gorman | Apr 12, 2023 | 4 min read

Immune cells and pain neurons form complex partnerships to protect our bodies from pathogens, new research reveals.

Using Digital Spatial Profiling for Transcriptomic Analysis of Neuronal Subpopulations

The Scientist Creative Services Team in collaboration with Advanced Cell Diagnostics | 1 min read

Kit Fuhrman and Anushka Dikshit present how to obtain whole transcriptome data from spatially mapped neuron populations.

Image of the fly brain (grey) highlighting the population of neurons (pink) to which the gut-secreted peptide CCHa1 signals

A Protein-Rich Diet Helps Mice and Flies Sleep More Soundly: Study

Alejandra Manjarrez, PhD | Mar 24, 2023 | 3 min read

The effect appears to be mediated by a gut-secreted peptide that signals to neurons in the brain that modulate the response to mechanical vibrations.

Complete model of fly brain neuron connections

How Larval Fruit Fly Brains Convert Sensory Signals to Movement

Laura Dattaro, Spectrum | Mar 10, 2023 | 4 min read

A wiring map diagrams more than half a million neuronal connections in the first complete connectome of Drosophila and holds clues about which brain architectures best support learning.

Mapping Neuronal Gene Expression to Understand Pain

The Scientist Creative Services Team in collaboration with Advanced Cell Diagnostics | 1 min read

Ted Price, Diana Tavares-Ferreira, and Stephanie Shiers discuss how mapping gene expression at the neuronal level provides insight into pain mechanisms and anti-pain drug development.

A cross-section of mouse brain showing the locus coeruleus in fluorescent green

Hormone Sobers Up Drunken Mice: Study

Alejandra Manjarrez, PhD | Mar 8, 2023 | 3 min read

A hormone naturally induced by alcohol consumption accelerates the recovery of mice after binge drinking by activating neurons involved in arousal and alertness.