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Illustration of a virus
Vaccines: Sex Matters
Male patients who recover from mild COVID-19 have baseline immune states primed to mount stronger responses to future challenges than female patients.
Vaccines: Sex Matters
Vaccines: Sex Matters

Male patients who recover from mild COVID-19 have baseline immune states primed to mount stronger responses to future challenges than female patients.

Male patients who recover from mild COVID-19 have baseline immune states primed to mount stronger responses to future challenges than female patients.

monocyte

An artistic rendering of SARS-CoV-2 made to look like stained glass
SARS-CoV-2 Infection Can Alter Future Immune Reponses
Niki Spahich, PhD | Feb 22, 2023 | 3 min read
Males recovered from mild COVID-19 have baseline immune states primed to mount stronger responses to future challenges.
3D medical illustration of peripheral blood cells: a lymphocyte (left) and a monocyte (right) surrounded by red blood cells.
PBMCs: Mononucleated and Multipurposed
Deanna MacNeil, PhD | Dec 16, 2022 | 4 min read
Researchers employ peripheral blood mononuclear cells (PBMCs) in clinical and academic applications related to the immune system and regenerative medicine.
Artist&rsquo;s rendition of multiple <em>Neisseria gonorrhoeae</em>, the bacteria that causes gonorrhea, depicted as two spheres stuck together, each covered in tendrils.
Gonorrhea-Blocking Mutation Also Protects Against Alzheimer’s: Study
Holly Barker, PhD | Aug 5, 2022 | 4 min read
Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.
Peripheral blood mononuclear cells surrounded by red blood cells in circulating blood.
Accelerating Immune Research with Cryopreserved Peripheral Blood Mononuclear Cells
The Scientist’s Creative Services Team and MilliporeSigma | Jul 18, 2022 | 3 min read
Commerically-available peripheral blood mononuclear cells offer a well-characterized, accessible, and consistent model for immunology and therapeutic development.
white mouse with pups
Doubts Raised Over Whether Mice Can Truly Inherit Immunity
David Adam | Jan 26, 2022 | 3 min read
An independent lab fails to replicate results suggesting mammals exposed to pathogens could pass on immunological protections through epigenetic mechanisms.
white adult mouse with 4 pups on white background
Mice that Survive Infection Pass on Stronger Immunity
David Adam | Oct 18, 2021 | 3 min read
Offspring of animals subjected to a real or simulated pathogen were more able to fend off disease, a study finds.
Infographic: How Vaccines Train Innate Immunity
Shawna Williams | Nov 1, 2020 | 1 min read
A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.
Special Report
covid-19 sars-cov-2 coronavirus pandemic immune response severity severe biomarkers prognostic predictor neutrophil monocyte myeloid cytokine interleukin
The Immune Hallmarks of Severe COVID-19
Katarina Zimmer | Sep 16, 2020 | 10+ min read
Researchers are trying to make sense of immune systems gone haywire and develop biomarkers to predict who will become the sickest from a coronavirus infection.
stroke, animal model, mouse model, blood, cytokine storm, immune system, immune response, MMP-9, neutrophil
Blood Replacement Rescues Mice from Stroke Damage
Amanda Heidt | Aug 31, 2020 | 5 min read
When mice that had suffered a stroke were given blood from a healthy donor, they experienced less tissue and neurological damage.
bcg tuberculosis tb sars-cov-2 covid-19 coronavirus pandemic vaccine nonspecific effects trained immunity innate immune system response
An Old TB Vaccine Finds New Life in Coronavirus Trials
Anthony King | May 4, 2020 | 8 min read
Studies are underway to test whether giving a shot of BCG vaccine could protect doctors and nurses against COVID-19.
blood vessel hydrogel microvasculature endothelium
Image of the Day: New Growth
Chia-Yi Hou | Apr 12, 2019 | 1 min read
Injection of a hydrogel that mechanically resembles a blood clot promotes the growth of new blood vessels in mice.
Exosomes Linked to Cancer Spread from Chemoresistant Tumors in Mice
Carolyn Wilke | Jan 10, 2019 | 4 min read
The vesicles promote metastasis after chemotherapy, but the authors say the results shouldn’t alarm patients and may point to ways to improve treatments.
Image of the Day: Brain, Heal Thyself
The Scientist Staff and The Scientist Staff | Apr 20, 2018 | 1 min read
When a mouse’s brain undergoes traumatic injury, immune cells clear the dead from the affected area, after which blood cells swoop in to repair blood vessels.
Researchers Uncover Previously Unknown Immune Cell Subtypes
Aggie Mika | Jul 16, 2017 | 2 min read
Using single-cell RNA sequencing, scientists characterize new populations of dendritic cells and monocytes.
Immunity in the Brain
Amanda B. Keener | Oct 31, 2016 | 2 min read
Researchers document the diverse roles of immune cells in neuronal health and disease.
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