miRNA

Matthew Disney’s idea of small molecules that target RNA once seemed fanciful. Now, even the pharma industry is pursuing it

The tiny strings of RNA promote translation of a protein implicated in cancer, a hint they could regulate gene expression in more ways than previously thought.

A study finds that plants sharing the same growth medium can exchange microRNAs that silence genes in the recipient, suggesting the nucleic acids may act as signaling molecules.

Renewed interest from the biotech industry sparks hope for drugging the nucleic acid to treat cancer and other conditions.

Exosomes produced by macrophages in fatty tissue influence insulin sensitivity in distant cell types, a study finds.

A braided structure and some adhesive hydrogel make therapeutic microRNAs both stable and sticky.

Instructor, Department of Systems Biology, University of Texas MD Anderson Cancer Center. Age: 38

Regulation of genome expression orchestrates the behavior of insect castes and the human response to social stress.

Researchers pinpoint microRNAs that could play a role in how Wolbachia bacteria manipulate their arthropod hosts.

Cellular blebs shed by tumor cells can process short stretches of RNA that go on to induce tumor formation in neighboring cells.

The Swiss pharmaceutical giant will reportedly pay $450 million for a Danish biotech company that develops drugs that silence microRNAs.

A mouse study shows that molecular remnants of early-life stress can be passed on to future generations.

Inhibiting a small regulatory RNA appears to improve cardiac function in mice with surgically induced heart problems.

Researchers identify microRNAs that keep cardiac cells healthy after heart attack, potentially paving the way for future heart regenerating therapies.

Associate Professor, Department of Urology, University of California, San Francisco. Age: 45