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The image shows many neurons in culture expressing the glutamate reporter iGluSnFR3 in green.
Biosensors Illuminate Talk Between Neurons
First developed in 2013, a fluorescent indicator has evolved to enable precise glutamate tracking.
Biosensors Illuminate Talk Between Neurons
Biosensors Illuminate Talk Between Neurons

First developed in 2013, a fluorescent indicator has evolved to enable precise glutamate tracking.

First developed in 2013, a fluorescent indicator has evolved to enable precise glutamate tracking.

methods and technology

A man sitting at a desk in a white lab coat holds up a large model of a <em >Drosophila</em> fly. In the background is a window and a bookcase.
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Illustration showing how iGluSnFR3, tracks glutamate release at the synapse level. Upon binding to glutamate, the reporter changes its conformation, intensifying the signal of its fluorescent protein.
Infographic: How a Glutamate Sensor Tracks Synapses
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 1 min read
A third generation glutamate sensor with a fluorescent readout offers insights into neuronal communication.
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