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Jumping Genes Put a Target on Cancerous Cells
Jumping Genes Put a Target on Cancerous Cells
Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.
Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.
mass spectrometry
Disease Scent Signatures Disclose What the Nose Knows
Iris Kulbatski, PhD | Jun 12, 2023 | 4 min read
Researchers redefine the lost art of smelling illness using one woman’s exquisitely sensitive nose.
Scientists Discover New “Superfast” Muscle Fibers in Mouse Limbs
Katherine Irving | Feb 9, 2023 | 4 min read
Fast twitch fibers like these could one day be used to treat diseases like Parkinson’s.
Best Practices for Single-Cell Proteomics Using Mass Spectrometry
The Scientist’s Creative Services Team | 1 min read
In this webinar, Runsheng Zheng and Fernanda Salvato will discuss how to optimally examine single-cell proteomes through label-free, data-independent acquisition (DIA) mass spectrometry.
Scientists Use Centrifuge to Discover a Hormone
Katherine Irving | Jan 23, 2023 | 3 min read
A new method for isolating extracellular fluid aims to discover molecules with therapeutic potential that were previously obscured by highly abundant proteins.
Amid the COVID-19 Pandemic, Some Scientists Bring the Bench Home
Emma Yasinski | May 13, 2020 | 5 min read
PCR moves into the laundry room, while insect colonies take up residence in the shower.
The Ins and Outs of LC-MS
Deanna MacNeil, PhD | 4 min read
From proteomics to pharmacokinetics, researchers turn to advances in liquid chromatography and mass spectrometry to identify and quantify components in different samples.
Lipid Expert and Babraham Institute Director Michael Wakelam Dies
Amy Schleunes | Apr 7, 2020 | 2 min read
Wakelam, who died of a suspected COVID-19 infection, is remembered for his research on the physiological function of lipids.
Chemicals on the Skin Could Enable Parkinson’s Detection
Shawna Williams | Mar 20, 2019 | 2 min read
Researchers teamed up with a woman with a keen sense of smell to identify telling differences between healthy people and those with the neurodegenerative disease.
Technique Talk: The Fundamentals of Mass Spectrometry-Based Proteomics
The Scientist’s Creative Services Team | 1 min read
Learn the basics of proteomics analysis and nanoLC-MS/MS data acquisition.
Could a Dose of Sunshine Make You Smarter?
Ruth Williams | May 17, 2018 | 3 min read
Moderate ultraviolet light exposure boosts the brainpower of mice thanks to increased production of the neurotransmitter glutamate.
Researchers Develop Potential Blood Test for Alzheimer’s Disease
Catherine Offord | Feb 1, 2018 | 2 min read
The test uses levels of plasma amyloid-β to estimate the buildup of protein plaques in the brain.
An Introductory Guide to Proteomics
Sejal Davla, PhD | 5 min read
Deconstructing concepts, approaches, and data analysis in proteomics workflows.
Mapping Brain Proteins
Devika G. Bansal | Feb 1, 2018 | 7 min read
Researchers are using souped-up mass spectrometry to localize proteins within brain cells.
2017 Top 10 Innovations
The Scientist Staff | Dec 1, 2017 | 10+ min read
From single-cell analysis to whole-genome sequencing, this year's best new products shine on many levels.
Solutions for mRNA Direct Sequence Mapping
Thermo Fisher Scientific | 1 min read
As mRNA therapeutics gain popularity, a novel solution for their development emerges.
Metabolomics Data Under Scrutiny
Ashley P. Taylor | Sep 15, 2017 | 4 min read
Out of 25,000 features originally detected by metabolic profiling of E. coli, fewer than 1,000 represent unique metabolites, a study finds.
Quantitating Glycans for Biomarker Discovery
Amanda Keener | Aug 27, 2017 | 8 min read
Techniques for comparing the relative abundances of glycans and glycoproteins in clinical samples
Proteomics: Pushing Towards Single-Cell Resolution
The Scientist’s Creative Services Team | 1 min read
Learn how the latest single-cell proteomics technology is revolutionizing protein analysis and driving research progress.
Top 10 Innovations 2016
The Scientist Staff | Dec 1, 2016 | 10+ min read
This year’s list of winners celebrates both large leaps and small (but important) steps in life science technology.