long noncoding RNA

A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males. 

Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.

Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.

Neurologically important noncoding RNAs come in many shapes and sizes.

The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.

A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.

Renewed interest from the biotech industry sparks hope for drugging the nucleic acid to treat cancer and other conditions.

Nearly 20,000 lncRNAs identified in human cells may play some role in cellular activities.

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.

An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.

Techniques for mapping chromosome conformation