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Human Blastocyst-Like Structures Made in the Lab
Human Blastocyst-Like Structures Made in the Lab
Two new papers describe the generation of so-called blastoids, which could avoid the use of embryonic cells and make studying early human development much more accessible.
Two new papers describe the generation of so-called blastoids, which could avoid the use of embryonic cells and make studying early human development much more accessible.
induced pluripotent stem cells
Majority of Respondents Support Chimeric Animal Research: Survey
Amanda Heidt | Oct 1, 2020 | 4 min read
Almost 60 percent of people in a new study on attitudes in the US felt comfortable using animals to grow human organs from induced pluripotent stem cells.
New iPSC Culture Medium Promises Weekends Off at Low Costs
Katarina Zimmer | Jan 20, 2020 | 5 min read
Biologists have published a DIY recipe for human induced pluripotent stem cell maintenance, which they estimate costs 3 percent of commercial media prices.
PBMCs: Mononucleated and Multipurposed
Deanna MacNeil, PhD | 4 min read
Researchers employ peripheral blood mononuclear cells (PBMCs) in clinical and academic applications related to the immune system and regenerative medicine.
Genes that Are Harmless on Their Own Cause Disease When Combined
Chia-Yi Hou | Sep 1, 2019 | 3 min read
A case study of a family demonstrates that different genetic mutations from the two parents cause severe heart disease symptoms in the children.
Human Cortical Organoids Model Neuronal Networks
Abby Olena, PhD | Aug 29, 2019 | 4 min read
After growing in culture for a few months, the mini-brains produced rhythmic neural activity that strengthened over time.
Brush Up: What Is Stemness and Pluripotency?
Deanna MacNeil, PhD | 4 min read
Scientists study pluripotent stems cells to understand early development and how to use them in regenerative medicine, disease modeling, and drug discovery.
Biotechs Race to Develop Stem Cell Treatments for Diabetes
Eric Bender | Jul 15, 2019 | 8 min read
Insulin-producing cells grown in the lab could offer a functional cure for the disease.
Donor-Derived iPS Cells Show Promise for Treating Eye Disease
Jef Akst | Apr 30, 2019 | 2 min read
Age-related macular degeneration patients who received injections of retinal cells derived from donors’ induced pluripotent stem cells have maintained their level of eyesight for a year.
A Guide for High-Throughput Screens with Pluripotent Stem Cells
The Scientist Creative Services Team in collaboration with Miltenyi Biotec | 1 min read
Experts discuss reliable high-throughput workflows for PSC-derived cellular screens
Stem Cell–Derived Neurons from People with Autism Grow Differently
Jef Akst | Jan 11, 2019 | 2 min read
Changes in gene expression also hint at how the brains of people with ASD develop differently from those of other people.
Trial Launched to Treat Parkinson’s with Reprogrammed Stem Cells
Diana Kwon | Jul 31, 2018 | 1 min read
Surgeons will inject approximately 5 million dopamine-producing progenitor cells into patients’ brains.
World’s First Commercial iPSC Cell Plant Opens in Japan
Jim Daley | Mar 23, 2018 | 2 min read
The $340 million, 30,000-square-foot center will produce cells for therapeutic applications.
Image of the Day: Hair Follicles
The Scientist Staff and The Scientist Staff | Feb 2, 2018 | 1 min read
Under certain conditions, skin organoids including hair follicles can be generated from mouse pluripotent stem cells, researchers report.
Induced Pluripotent Stem Cells Show Signs of Donor Age
Ashley P. Taylor | Dec 12, 2016 | 3 min read
iPSCs created through the reprogramming of human somatic cells retain genomic marks of the donor’s age.
Week in Review: October 17–21
Jef Akst | Oct 20, 2016 | 2 min read
Report finds that pathologist involved in anonymous defamation case committed multiple acts of misconduct; growing eggs from stem cells; neutrophils’ role in metastasis; convergent evolution in birds
Review: The End of Sex
Tanya Lewis | May 13, 2016 | 2 min read
Legal expert Henry Greely envisions a world in which advances in biotechnology obviate the need for sexual reproduction as we know it.
With CRISPR, Modeling Disease in Mini Organs
Tanya Lewis | May 6, 2016 | 3 min read
Organoids grown from genetically edited stem cells are giving scientists a new tool to screen drugs and test treatments.
Skin Cells Turned Into Immature Sperm
Tanya Lewis | Apr 29, 2016 | 1 min read
The reprogrammed germ-like cells were unable to fertilize eggs, however.
Hairy Skin from Stem Cells
Tanya Lewis | Apr 5, 2016 | 6 min read
Researchers create lab-grown mouse skin complete with hair follicles and sweat glands.