Login
Subscribe
“Smarter” CAR T Cells Target Tumors with Precision
“Smarter” CAR T Cells Target Tumors with Precision
Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T–based treatments.
Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T–based treatments.
immunosuppression
Thwarting AAV-Neutralizing Antibodies Could Improve Gene Therapy
Emma Yasinski | Sep 25, 2020 | 5 min read
Adeno-associated viral vectors can deliver gene therapies, but AAV-neutralizing antibodies might prevent the medicines from working.
Measles Leaves the Immune System Vulnerable to Other Diseases
Ruth Williams | Oct 31, 2019 | 4 min read
Two studies present biological evidence that measles infections in unvaccinated children wipe out immune memories of other pathogens, putting the kids at risk of other deadly diseases.
PD-L1 in Extracellular Vesicles May Help Glioblastoma Evade Immunotherapies
Jim Daley | Mar 8, 2018 | 2 min read
The discovery suggests that the immune checkpoint can operate at a further distance from tumor cells than previously believed.
Immune Checkpoint Found Lacking in Type 1 Diabetes
Ruth Williams | Nov 15, 2017 | 3 min read
Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.
An Immunological Timeline for Pregnancy
Catherine Offord | Sep 1, 2017 | 4 min read
A new study uses blood samples from pregnant women to track changes in the immune system leading up to birth, and predicts gestational age from the mothers’ immune signatures.
Inhibiting Sperm Protein Causes Infertility
Karen Zusi | Oct 5, 2015 | 2 min read
Two drugs targeting a protein in sperm cause reversible infertility in male mice, providing new hope for a male contraceptive.
Done with Immunosuppressants
Jef Akst | Jul 3, 2014 | 2 min read
Adult sickle-cell patients have safely stopped taking their immunosuppressant medication thanks to a new type of blood stem-cell transplant.
T cells and Transplantation
Ruth Williams | Nov 13, 2013 | 3 min read
Drug-resistant immune cells protect patients from graft-versus-host disease after bone marrow transplant.
Transplant Without Drugs?
Edyta Zielinska | Mar 8, 2012 | 1 min read
A new method for transplanting immunologically mismatched organs may remove the need for life-long immunosuppressive drugs to prevent rejection.