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immunology

T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
Fluorescent images of red cells showing high and low levels of infection in green
Parasite Drove Natural Selection in Amazonian Indigenous Groups
Natalia Mesa, PhD | Mar 13, 2023 | 4 min read
The findings could help researchers understand why some individuals are more vulnerable to deadly Chagas disease.
3D rendered image of multiple antibody-drug conjugate next generation antibodies.
Advances in Antibody Therapeutics
Elina Kadriu | 4 min read
Scientists engineer therapeutic antibodies with improved stability and efficacy. 
neuron surrounded by immune cells
Meningitis Bacteria Trigger Headaches, Then Sneak Into the Brain
Natalia Mesa, PhD | Mar 6, 2023 | 3 min read
Researchers find that bacteria stimulate a headache-causing pain pathway to suppress the immune system and infect the brain. 
Illustration of woman looking at floating cells through a telescope
Opinion: New Diabetes Drug Signals Shift to Preventing Autoimmunity
Jane Buckner, MD and Carla Greenbaum, MD | Mar 1, 2023 | 4 min read
A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.
A Spotlight on Cancer Cell Metabolism
A Spotlight on Cancer Cell Metabolism
The Scientist’s Creative Services Team | 1 min read
In this webinar, Elena Piskounova and Christina Towers discuss the implications of metabolic changes in cancer cells for therapeutic development and efficacy. 
Dead shark on concrete
Researchers Make Alternatives to Shark-Sourced Vaccine Ingredient
Natalia Mesa, PhD | Feb 22, 2023 | 3 min read
Synthetic variations of squalene, which is used to boost immune responses, could make vaccines more effective while reducing fisheries for struggling sharks.
An artistic rendering of SARS-CoV-2 made to look like stained glass
SARS-CoV-2 Infection Can Alter Future Immune Reponses
Niki Spahich, PhD | Feb 22, 2023 | 3 min read
Males recovered from mild COVID-19 have baseline immune states primed to mount stronger responses to future challenges.
Efficient and Flexible Spatial Multiplexing: Assay Development Guidelines for ChipCytometryTM
Efficient and Flexible Spatial Multiplexing: Assay Development Guidelines for ChipCytometryTM
The Scientist’s Creative Services Team | 1 min read
In this webinar, Karen Kwarta will discuss advancements in cellular multiplexing assay technology.
RSV vaccine design concept art
RSV Vaccines That Work?
Rachael Moeller Gorman | Feb 16, 2023 | 10+ min read
Multiple candidates are in Phase 3 clinical trials for older adults and pregnant women, with some getting close to approval in the United States.
Red T cell
Jumping Genes Put a Target on Cancerous Cells
Natalia Mesa, PhD | Feb 14, 2023 | 4 min read
Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.
TSS
Immune Cells and ALS: A Balance Between Life and Death
The Scientist’s Creative Services Team | 1 min read
Understanding the role of immune cells in neurodegeneration may help scientists develop new diagnostic, prognostic, and treatment tools.
Fluorescence image in purple and green of lymph node
Targeting Antigen “Sanctuary” in Lymph Nodes Could Make Vaccines Better
Natalia Mesa, PhD | Feb 10, 2023 | 3 min read
Researchers find that small sacks inside lymph nodes contain low proteolytic activity and act as safe havens for antigens.
Artist’s rendering of various orange and pink colored bacteria
Q&A: What if Immune Cells Don’t Actually Detect Viruses and Bacteria?
Dan Robitzski | Feb 3, 2023 | 10+ min read
The Scientist spoke with Jonathan Kagan about his idea that immune cells respond to “errors” made by unsuccessful pathogens, not the pathogens themselves.
How Gut Microbiomes Shape Anti-Tumor Immune Responses
How Gut Microbiomes Shape Anti-Tumor Immune Responses
The Scientist’s Creative Services Team | 1 min read
In this webinar, Andrew Y. Koh will discuss the role of the gut microbiome in modulating cancer immunotherapy. 
Closeup of a pair of hands in blue gloves holding a white mouse and injecting it with an amber colored liquid.
Opioids Recruit the Immune System to Cause Withdrawal Symptoms
Dan Robitzski | Jan 25, 2023 | 6 min read
A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.
Human brain stock photo
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment
Deanna MacNeil, PhD | Jan 23, 2023 | 3 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
Neoantigen Prediction for Precision Immunotherapies
Neoantigen Prediction for Precision Immunotherapies 
The Scientist’s Creative Services Team | 2 min read
Learn about the tools and resources researchers use to define, discover, and deploy anti-tumor immunotherapies.
three black mice lined up next to each other. the one on the left, fed a low-fat diet, has one small bald patch, the middle mouse, fed fish oil, has a large bald spot across its shoulders and back, and the right mouse, fed cocoa butter, has no baldness.
Fish Oil in Diet Can Cause Hair Loss in Mice, Study Finds
Katherine Irving | Jan 19, 2023 | 3 min read
The oil’s omega-3 fatty acids accumulate in the mice’s skin, triggering an immune response that causes hair loss.
An artist’s rendering of a DNA-based virus trap, represented as gray rods in a short cone-shaped arrangement. One is coated with blue molecules, likely antibodies, that adhere to a virus target. Another image shows to traps coming together to capture a red coronavirus.
“Origami” DNA Traps Could Keep Large Viruses From Infecting Cells
Natalia Mesa, PhD | Jan 18, 2023 | 4 min read
By engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells.
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