immunity

In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.

Researchers find that small sacks inside lymph nodes contain low proteolytic activity and act as safe havens for antigens.

Researchers find signatures pre- and post-vaccination that correlate with a more robust immune response. 

A high-fat diet induced changes to the animals’ vaginal microbiomes that boosted survival after exposure to the virus.

When fused to RSV, influenza A virus is better able to escape antibodies that usually neutralize it, an in vitro study finds.

A new study points to repercussions of the Medieval pandemic for the health of modern humans.

The National Institute of Allergy and Infectious Diseases was not aware that the work involved a chimeric strain of SARS-CoV-2, STAT reports.

Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.

Researchers made the find using an algorithm that purportedly distinguishes between mutations that were selected for and those that came along for the ride by coincidence, a feat that has long eluded scientists.

Acute stress makes immune cells migrate immediately to the bone marrow, which prepares the body for injury at the expense of increasing infectious disease susceptibility.

Several mechanisms contribute to the increased transmissibility of this SARS-CoV-2 variant.

Dozens of intranasally delivered vaccines targeting SARS-CoV-2 are in development. Could they pave the way for widespread nasal vaccination in the future?

Researchers find that tissue-resident memory T cells in the corneas of mice engender a lasting immune response.

A study identifies a gene that appears to be partially responsible for the health effects of a limited diet.

Two recent papers provide insight into possible risk factors for developing the chronic condition, including autoantibodies and diabetes.

An independent lab fails to replicate results suggesting mammals exposed to pathogens could pass on immunological protections through epigenetic mechanisms.

Researchers continue to debate whether US President Abraham Lincoln was coming down with smallpox as he delivered his famous Gettysburg Address, and if he had been immunized.

Researchers find that the protective outer layer that lungfish make to survive extended dry periods—once thought to be a simple mucus shell—contains immune cells that trap bacteria and protect the animals from infection.