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Capturing the Brain Tumor Microenvironment with Tissue Engineering
Capturing the Brain Tumor Microenvironment with Tissue Engineering
Researchers built a 3D glioblastoma model to study therapeutic resistance and improve drug screening systems.
Researchers built a 3D glioblastoma model to study therapeutic resistance and improve drug screening systems.
glioblastoma
Machine Learning for Predicting Glioblastoma Prognosis
Tanvir Khan, PhD | Oct 4, 2023 | 3 min read
Researchers integrate scRNA-seq, spatial transcriptomics, and histology imaging data to show that spatial cellular architecture predicts glioblastoma prognosis.
Turning up the Heat on Brain Tumors
Aparna Nathan, PhD | Jul 17, 2023 | 3 min read
Oncolytic viruses can help glioblastoma respond to immunotherapy.
Building Cancer Models with Creative Collaborators
Deanna MacNeil, PhD | 1 min read
Jennifer Munson shares how teamwork and collaboration have fostered her research at the intersection of creativity and clinical discovery.
Electric Fields Disrupt Cancer Cell Division
Danielle Gerhard, PhD | May 4, 2023 | 5 min read
A novel, non-invasive treatment using electrical currents exploits physiological properties of dividing cancer cells to prolong survival and augment current therapies.
Our Favorite Neuroscience Stories of 2022
Dan Robitzski | Dec 28, 2022 | 4 min read
This year, neuroscience researchers made important discoveries related to how neurodegeneration attacks the human brain, hooked cultured neurons up to machinery to teach them to play a video game, and more.
Stem Cell Engineering for Tissue Regeneration
The Scientist’s Creative Services Team | 1 min read
Innovative strategies drive stem cell repair of organ damage.
Caught on Camera
The Scientist Staff | Dec 12, 2022 | 4 min read
See some of the coolest images recently featured by The Scientist.
Astrocytes Feed Glioblastoma, Promoting Tumor Growth: Mouse Study
Patience Asanga | Oct 5, 2022 | 3 min read
Starving glioblastoma tumors of the cholesterol made by astrocytes could suppress brain cancer progression.
The Structure and Functions of the p53 Pathway: Information Acquisition, Redundancy, and Connectivity
The Scientist’s Creative Services Team | 1 min read
Arnold Levine will discuss his discovery of p53 and the evolution of the field since then, and Jon Chen will discuss the use of single-cell phosphoproteomics in identifying changes in key signaling networks, including p53.
Glioblastoma Cells Imitate Immature Neurons to Invade the Brain
Sophie Fessl, PhD | Aug 5, 2022 | 3 min read
Neuron-like glioblastoma cells are the pioneers of deadly tumors’ spread through the brain, contributing to their devastating invasiveness, a study in mice finds.
A New Model with Fully Functioning Blood Vessels Mimics Brain Cancer
Roni Dengler, PhD | Sep 10, 2021 | 2 min read
A newly developed platform may one day replace cell culture and animal models to personalize cancer treatment.
Molecular Imaging Pioneer, Sanjiv “Sam” Gambhir, Dies at 57
Lisa Winter | Jul 28, 2020 | 3 min read
The Stanford Medical School professor’s research aided the development of positron emission tomography (PET) reporters to identify disease.
Zika as Cancer Buster?
Amy Schleunes | Apr 1, 2020 | 2 min read
By infecting glioblastoma cells but not healthy brain tissue, some form of the virus could serve a therapeutic purpose.
CAR T Cell Adds Scorpion Venom to Tackle Tumor Heterogeneity
Amy Schleunes | Mar 24, 2020 | 5 min read
A newly engineered CAR T cell that incorporates a peptide isolated from the venom of the deathstalker scorpion has broad brain tumor–binding capabilities that will be investigated in an upcoming clinical trial.
Air Pollution Tied to Brain Cancer: Study
Emily Makowski | Nov 13, 2019 | 2 min read
Inhaling combustion-produced particles may lead to the development of brain tumors.
Immune-Activating Gene Therapy for Glioblastoma
Ruth Williams | Aug 14, 2019 | 3 min read
The results of an early trial in 31 brain cancer patients finds immune activity boosted in the tumor, and possibly longer survival.
Glioblastoma on a Chip
Jef Akst | Jul 15, 2019 | 3 min read
Researchers use 3-D printing technology to construct a brain cancer model that accurately recapitulated in vivo biology and predicted patient drug responses.
Infographic: A 3-D Printed Brain Tumor
Jef Akst | Jul 15, 2019 | 1 min read
How researchers create a glioblastoma on a chip that can predict patients’ response to treatments
Why Is Cancer More Common in Men Than in Women?
Jef Akst | Apr 1, 2019 | 4 min read
The molecular processes that lead males to be more susceptible to the disease are only beginning to come to light.