Mice lacking the RNA had deregulated microRNAs in the brain, disrupted synaptic communication, and behavioral abnormalities associated with neuropsychiatric disorders.
Recent research has revealed many surprises about circular RNAs, from findings that they are translated in vivo to links between their expression and disease.
Circular RNA biogenesis occurs when RNA fragments are bent into closed loops of one or more exons and/or introns.
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