cellular reprogramming

Various microbes, including several human pathogens, hijack the cell’s skeleton, membranes, and protein-making machinery to make themselves at home.

Unlike biotech tools adapted from nature, the invention was entirely conceived by humans and represents one of the few proteins made from scratch in the lab.

Reprogrammed cells fix wounds in living mice.

By converting glial cells into dopaminergic neurons, scientists were able to partially rescue motor behavior in mice.

Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.

The animals, some of which were cloned from the same tissue as Dolly, appeared as healthy as non-cloned sheep, a study suggests.

A new tool makes programming living cells like writing computer software.

Compared to induced pluripotent stem cells generated from somatic cells, stem cells created by nuclear transfer appear to be closer to the genetic state of embryonic cells.

Study confirms that somatic cell nuclear transfer, an alternate method of creating patient-specific pluripotent stem cells, can be used to reprogram adult cells.

Meet some of the people featured in the March 2014 issue of The Scientist.