cell therapy

Researchers track neural connections between retinal cells in a dish to understand their therapeutic potential.

Susan Thomas discusses how her team engineered a microfluidic device to screen for T cells with improved homing capability to tumor cells. 

This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.

A new benchtop microfluidic device generates patient-derived tumor micro-organospheres that allow for real-time cancer therapy decisions.

Heated gold nanoparticles unleash the therapeutic activity of engineered CAR T cells.

Transplanted CAR stem cells persisted long term and showed multilineage engraftment in tissues that harbor HIV.

Researchers developed a new CAR T-cell therapy that targets specific growth factor receptors in glioblastoma to eliminate brain tumors.

Pairing CARs with a synthetic receptor makes T cells more lethal tumor killers.

Researchers propose that an infusion of memory T cells from people who have recovered from SARS-CoV-2 infections could treat severe disease.

As the first clinical data become available on treating coronavirus patients with the cells, scientists are equivocal about the rationale for the intervention.

The immunotherapy induces a form of cell death in leukemia cells in mice that triggers cytokine release syndrome, a dangerous inflammatory reaction that occurs in some patients.

To advance the possibility of off-the-shelf cardiac cell therapies, scientists devise an engineered cardiac stem cell that avoids stimulating a detrimental immune attack.

Several early-stage clinical trials indicate that implanting patients with the cells is safe. But whether they can alleviate neurological problems remains to be seen.