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cancer research

3D rendered medical illustration of T cells trying to subdue cancer cells.

How Tumors Tire Out T Cells

PhenomeX | Jul 19, 2023 | 1 min read

Researchers investigated how cancer antigenicity drives unique forms of T cell exhaustion and hypofunctionality.

Tasmanian Devils Face Threats from Rapidly Evolving Facial Cancers

Natalia Mesa, PhD | Jun 30, 2023 | 3 min read

A genetic study tracked the evolution of two transmissible cancers currently ravaging populations of Tasmanian devils.

CAR Technology in Cancer Therapy: From CAR-T to CAR-NK

The Scientist’s Creative Services Team and Sino Biological | 4 min read

From early target discovery to preclinical development stages, researchers explore novel strategies for effective cell therapies in cancer treatment.

Green and brown illustration of cancer cells in front of a peach and yellow background.

Bacterial Tractor Beams Bring Radiation to Tumors

Rachael Moeller Gorman | Apr 17, 2023 | 3 min read

Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.

Cancer Cells Gather Speed in Thicker Fluids

Holly Barker, PhD | Nov 22, 2022 | 4 min read

Viscous solutions accelerate the migration of tumor cells and may enable metastasis, according to a new study.

From histopathology to multiplex immunohistochemistry and spatial transcriptomics, learn how to obtain the appropriate profiling depth to match cancer classification needs.

Broadening Tumor Molecular Profiling Horizons

Canopy Biosciences | 1 min read

From histopathology to multiplex immunohistochemistry and spatial transcriptomics, learn how to obtain the appropriate profiling depth to match cancer classification needs.

A purple-stained section of an invasive breast cancer growth. The dark purple non-fatty tissue takes up the majority of the frame, and pale purple circular tumors grow in ducts in the bottom left.

Harboring Hard and Soft Cells Lets Tumors Grow and Metastasize Simultaneously

Katherine Irving | Oct 17, 2022 | 4 min read

Islands of rigid cells within a matrix of soft ones allow tumors to be both solid and fluid, granting them toughness without losing the ability to break apart.

exterior of Fred Hutch research building

Fred Hutch Receives $710 Million Gift from the Bezos Family

Shawna Williams | Oct 13, 2022 | 1 min read

The donation will fund recruitment, research facilities, clinical research, and immunotherapy research.

Setting Better Traps for PARP Inhibitors

The Scientist’s Creative Services Team and BPS Bioscience | 4 min read

An innovative assay permits researchers to screen for small molecule PARP inhibitors that trap the enzyme on DNA and selectively execute cancer cells.

illustration of blue cells with exosomes budding off of them and floating away

Nanoparticles Spur Mouse Immune System to Attack Cancer

Shafaq Zia | Sep 13, 2022 | 2 min read

A study finds that engineered exosomes are effective in mice, but their potential use in humans raises safety questions.

Renee Wegrzyn Tapped to Head ARPA-H

Andy Carstens | Sep 12, 2022 | 2 min read

As the new agency’s director, the DARPA veteran will spearhead a high-risk, high-reward approach to biomedical research.

Enhancing the Efficacy of CAR-T Cell Therapies

The Scientist Creative Services Team in Collaboration with IsoPlexis | 1 min read

Jessica Morris will discuss strategies to improve CAR-T cell targeting, activation, and killing capabilities.

Histological slide showing cancerous prostate tissue

2D Genetic Map of Prostate Cells Charts Cancer Growth

Holly Barker, PhD | Aug 23, 2022 | 4 min read

An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.

Monica Bertagnolli standing in a hallway

White House Names Monica Bertagnolli as NCI Director

Andy Carstens | Aug 10, 2022 | 2 min read

The announcement confirms earlier reports that Bertagnolli will become the first woman to lead the National Cancer Institute since its founding in 1937.

Best of Cancer Research

The Scientist’s Creative Services Team | 1 min read

This collection of articles from The Scientist explores some of the latest cancer research!

black-and-white brain scan showing tumor

Glioblastoma Cells Imitate Immature Neurons to Invade the Brain

Sophie Fessl, PhD | Aug 5, 2022 | 3 min read

Neuron-like glioblastoma cells are the pioneers of deadly tumors’ spread through the brain, contributing to their devastating invasiveness, a study in mice finds.

Artist’s 3D rendering of malignant cancer cells, illustrated in pink, as it would appear under a scanning electron microscope.

Underdog Enzyme Likely Responsible for Mutations in Most Cancers

Sophie Fessl, PhD | Jul 28, 2022 | 3 min read

A previously overlooked enzyme called APOBEC3A is linked to the most prevalent mutational signatures in cancer cell lines, a study finds.

Genetic and Spatial Heterogeneity in Human Papillomavirus-Associated Oropharyngeal Cancer

The Scientist’s Creative Services Team | 1 min read

Joseph Powell will discuss how heterogeneous subpopulations of HPV+ head and neck cancer cells drive unique disease states, cell-cell interactions, and microenvironment dynamics, and have implications for cancer behavior, metastasis, and response to treatment.

An illustration of a mitochondrion, represented by a purple and orange bilayer, synthesizing reddish molecules of ATP.

Mitochondrial Protein Fuels Spread of Head and Neck Cancer

Patience Asanga | Jul 8, 2022 | 3 min read

Head and neck cancer cells lacking the peptide involved in energy production were less likely to metastasize in mice.