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cancer cell lines

electron micrograph of grey cancer cell, with two red T cells stuck to the side

Translation of “Jumping Genes” Creates Cancer Therapy Targets

Natalia Mesa, PhD | Mar 29, 2023 | 4 min read

Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.

Jumping Genes Put a Target on Cancerous Cells

Natalia Mesa, PhD | Feb 14, 2023 | 4 min read

Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.

Defined Primary Cell Culture and Media

The Scientist Creative Services Team in collaboration with MilliporeSigma | 3 min read

A new partnership opens the door for a source of highly purified human primary cells and defined cell culture media.

Vector image of swarming locusts in a field

Scents and Sense-Abilities: Using Bug Brainpower to Smell Cancer

Iris Kulbatski, PhD | Dec 12, 2022 | 4 min read

Scientists use locust brains as living biosensors to perform cancer cell breath tests.

Blue 3D illustration of X-shaped chromosomes

X Chromosome Silenced in Some Cancers in Males

Natalia Mesa, PhD | Nov 11, 2022 | 3 min read

A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males.

Artist’s 3D rendering of malignant cancer cells, illustrated in pink, as it would appear under a scanning electron microscope.

Underdog Enzyme Likely Responsible for Mutations in Most Cancers

Sophie Fessl, PhD | Jul 28, 2022 | 3 min read

A previously overlooked enzyme called APOBEC3A is linked to the most prevalent mutational signatures in cancer cell lines, a study finds.

line illustration of DNA with single-strand break

Cancer Cells Break Own DNA to Defend Against Radiation

Sophie Fessl, PhD | Apr 28, 2022 | 3 min read

Self-inflicted DNA breaks let the cells hit pause on repair of radiation-induced DNA damage, giving them time to recover, an in vitro study shows.

Henrietta Lacks Estate Sues Thermo Fisher over HeLa Cell Line

Catherine Offord | Oct 4, 2021 | 3 min read

Attorneys for the family seek compensation for the company’s sale of cells cloned from tissue removed without consent by doctors at Johns Hopkins Hospital 70 years ago.

A view of the nucleus of a cell with DNA in blue, RNA in pink, and associated proteins in yellow and purple

DNA Methylation Influences Replication and Genome Organization

Abby Olena, PhD | Sep 22, 2021 | 3 min read

A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.

visualization of p53 protein interacting with its inhibitors MDM2 and MDMX

p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study

Marcus A. Banks | Jul 29, 2021 | 4 min read

New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.