C. elegans

Parents’ mutations, even if they’re not inherited by offspring, could affect subsequent generations through changes to epigenetic marks, a study finds.

Researchers say there may be similar, human genes whose effects on lifespan vary by sex.

Increasing mitochondrial activity in worms by engineering a light-activated proton pump into the organelle’s membrane extends the animals’ lifespan without evidence of health decline, according to a preprint.

The Scientist spoke to Mount Desert Island Biological Laboratory’s Jim Strickland about the institute’s new MDI Bioscience initiative to perform more drug testing and development in nonmammalian models.

A study shows “sonogenetics” could be a useful new tool in neuroscience and other fields.

Researchers identified a novel mechanism by which chemically induced stress is “remembered” by the mitochondria of worms more than 50 generations after the original trigger.

Neurons stressed with chemicals produce Wnt, which in turn triggers changes in the germline.

Worms, flies, and yeast live longer if the fidelity of their protein-making machinery is improved, a study shows.

A controversial idea from the mid-20th century is attracting renewed attention from researchers developing theories for how cognition arises with or without a brain.

The roundworm uses cues from visible light to help avoid eating toxic bacteria with a distinguishing hue.

The Yale neuroscientist seeks to understand the brain’s architecture and function using C. elegans.

A phthalate commonly found in shampoos, cosmetics, and cleaning products disrupts reproduction in worms.

Working with bacteriophages and nematodes, the University of California, Berkeley, molecular biologist uncovered a role for genetic switches in early development.

A small RNA in Pseudomonas triggers an avoidance response in C. elegans that can be passed on to the next generation, according to research presented at this week’s meeting of the American Society for Cell Biology.

A single-cell map of C. elegans’s transcriptome during development finds cell lineages that start out genetically different and end up as cells of similar function and genetic profile.

This newly described behavior occurs spontaneously, but can be modulated by food availability, temperature, and the size of the chambers.

A major sensory neuron in roundworms distinguishes proprioception from harmful touch by sending out local or whole-cell signals, respectively.

Worms with the reproduction-related TCER-1 gene deleted could fight off infection for longer and survived better when exposed to heat and radiation.

The connectomes trace 385 neurons in the male worm and 302 neurons in the hermaphrodite worm.