apoptosis

During development, neurons trim hundreds of excess axons in an intricately coordinated destructive process.

A wireless brain implant inhibits tumor growth in rats, overcoming many design flaws of current devices used to treat glioblastoma.

An unexpected find shows that sweet-sensing receptors also help epithelial cells in Drosophila larvae stay alive amid proteotoxic stress.

Scientists found that combining the notoriously flimsy anticancer protein p53 with a domain from a spider silk protein resulted in a more stable hybrid that’s more potent and easier for cells to synthesize.

Though scientists don’t yet know much about it, a newly described process called erebosis might have profound implications for how the gut maintains itself.

Self-inflicted DNA breaks let the cells hit pause on repair of radiation-induced DNA damage, giving them time to recover, an in vitro study shows.

In vitro and mouse experiments show how cancer cells forced through tiny pores—mimicking the physical experience of metastasis—resisted programmed cell death and avoided detection by the immune cells that would normally kill them.

A new study reports that human colon cancer cells at imminent risk of death can instead develop characteristics needed to colonize new parts of the body.

Using a transgenic fruit fly model, researchers demonstrate how epithelial barriers are maintained in living organisms despite high levels of cell turnover and death.

Researchers develop a caspase inhibitor that only works after being irradiated with UV light, giving them control over apoptosis in human cells.

A new inhibitor gives researchers the ability to control programmed cell death in cultured human T cells.

The Yale neuroscientist seeks to understand the brain’s architecture and function using C. elegans.

Introducing either necroptotic cells or an enzyme that triggers necroptosis can wipe out cancer.

Telomeres in cancer cells exposed to oxidative stress got shorter and stickier.

When hair follicle stem cells lose their protein-based death cue, they take on a new role helping to repair wounds in skin.