antigens

Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.

Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.

Researchers find that small sacks inside lymph nodes contain low proteolytic activity and act as safe havens for antigens.

Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.

Anecdotal reports and results from small studies on the diagnostics’ accuracy have prompted questions about the devices’ usage with the new variant, but researchers say more data are needed and emphasize the continued importance of SARS-CoV-2 testing.

Researchers find traces of SARS-CoV-2 in the stool and blood of kids with the post–COVID-19 inflammatory disorder, and signs of increased intestinal permeability.

These rapid tests could allow people to find out quickly and easily if they have the disease—if they get regulatory approval for the consumer market.

The Johns Hopkins University researcher bucked the prevailing idea that the body would not launch an immune response against its own tissues, and in doing so established an entirely new scientific discipline.

The Oxford researcher’s work on lipid and peptide antigens revealed key mechanisms in inflammation, immunotherapy, and vaccination, which are being pursued in clinical trial treatments.

A rogue hybrid lymphocyte, bearing characteristics of both B and T cells, may play a role in driving autoimmunity in the disease, although the mechanism is far from clear.

Researchers found that allegedly noncoding genetic material carries the instructions for many peptides that may help harness the immune system to fight cancer.

A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling.