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Overcoming Cancer Therapy Obstacles With Epitope Editing
Overcoming Cancer Therapy Obstacles With Epitope Editing
Editing epitopes expressed on the surfaces of transplanted hematopoietic stem cells renders them resistant to AML treatments without affecting their critical functions.
Editing epitopes expressed on the surfaces of transplanted hematopoietic stem cells renders them resistant to AML treatments without affecting their critical functions.
acute myeloid leukemia
Understanding the Blood Cancer Genomic Landscape
The Scientist’s Creative Services Team | Dec 13, 2022 | 1 min read
Information about the genomic and immunological characteristics of blood cancers is helping scientists discover and develop new immunotherapies.
Gene Therapy for Sickle Cell Not Linked to Cancer, Bluebird Finds
Lisa Winter | Mar 11, 2021 | 2 min read
Clinical trials were halted after the treatment’s vector that ferries in the healthy genetic sequence was identified in the genome of a patient’s cancer cells.
Baking Soda Boosts T Cells’ Ability to Fight Leukemia
Rachael Moeller Gorman | Nov 2, 2020 | 4 min read
Infusions of donor T cells to fight the cancer often fail, but sodium bicarbonate can counter lactic acid produced by leukemia cells, potentially improving remission rates in mice and humans.
Leukemia Relapses May Arise From Specialized Cells
Sukanya Charuchandra | Dec 1, 2018 | 2 min read
Targeting the transient group of cells could prevent recurrence of the disease.
Vitamin C Blocks Leukemia Progression in Mice
Aggie Mika | Aug 17, 2017 | 3 min read
High-dose vitamin C injections reverse the effects of a leukemia-promoting genetic deficiency.
$1.5 Billion Pharma Buyout for Leukemia Drug
Jef Akst | Jun 1, 2016 | 1 min read
Jazz Pharmaceuticals is set to purchase Celator to acquire an experimental treatment for acute myeloid leukemia.
Epigenetic Cancer Therapy Clears Phase I
Tracy Vence | Apr 7, 2014 | 2 min read
Investigational drug that inhibits proteins involved with epigenetic regulation shows activity against certain blood cancers in an early-stage clinical trial.
Telomeres in Disease
Rodrigo Calado and Neal Young | May 1, 2012 | 10+ min read
Telomeres have been linked to numerous diseases over the years, but how exactly short telomeres cause diseases and how medicine can prevent telomere erosion are still up for debate.
High-Tech Choir Master
Karen Hopkin | Jan 1, 2012 | 8 min read
Elaine Mardis can make DNA sequencers sing, generating genome data that shed light on evolution and disease.
Interfering with Cancer
Katherine Hyde and Paul Liu | Jan 1, 2011 | 4 min read
MicroRNAs may drive the development of leukemia.