B cells

Recent studies have lent support for a variety of hypotheses explaining the debilitating symptoms affecting millions of people after SARS-CoV-2 infection.  

A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.

For the first time, researchers performed a head-to head longitudinal study comparing the immune response elicited by mRNA and traditional COVID-19 vaccines to primary infections.

Compared to mice who got the doses in separate limbs, animals receiving flu shots in the same paw for both a first and second dose had better-trained memory B cells that bound tighter to the vaccine antigen.

A guide to mRNA-based cancer vaccines and where they’re headed next

A trio of papers shows that specialized antibodies can direct T cells to destroy cells that display portions of mutant cancer-related proteins, as well as T cells that have become cancerous themselves.

Half a year after infection, people who had recovered from COVID-19 had robust antibodies, along with traces of the virus in their gut, which may drive long-lasting immunity.

Outcomes in COVID-19 patients may be better in those recently infected with endemic coronaviruses. 

Through his studies on cancer-causing viruses, the University of California, Los Angeles, professor has helped develop lifesaving treatments.

Researchers report they’ve found a way to restore immune function in infants with one form of “bubble boy disease.”

Type I interferon organizes several immune mechanisms to suppress B cell responses to a chronic viral infection.

Using proteomics methods to inform antigen selection

The status of a person’s immune system can predict when a seasonal flu vaccination will not provide sufficient protection, according to a study. 

Researchers identify a subset of proinflammatory cytokine-producing B cells that may spark multiple sclerosis-related inflammation.